Tirzepatide

Tirzepatide is an FDA-approved injectable medication that works as a dual GLP-1 and GIP receptor agonist. It is used primarily for type 2 diabetes and obesity/weight management.

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Research Overview

Key Benefits

  1. Significant Weight Loss
    • Clinical trials show 15–22% average body weight reduction over 72 weeks in people with obesity.
    • Outperforms many other GLP-1–based therapies in weight-loss magnitude.
  2. Improved Blood Sugar Control
    • Lowers HbA1c by up to 2% or more in type 2 diabetes.
    • Enhances insulin sensitivity and reduces post-meal glucose spikes.
  3. Cardiometabolic Health
    • Improves cholesterol and triglyceride levels.
    • Modestly lowers blood pressure.
    • May reduce long-term cardiovascular risk.

Important Notes

  • Should be used under medical supervision, especially in patients with a history of pancreatitis or certain thyroid cancers.